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Customer Profiles
March 29, 2023

Using scRNA-Seq to Analyze the Effects of Lung Inflammation in SARS-Cov-2 Patients

Imagine that as a young scientist you saw a formerly fatal illness become treatable. Now, imagine that major contributors to this groundbreaking result become your mentors. It happened to Dr. Alejandro Pezzulo, MD, an Assistant Professor of Internal and Pulmonary Medicine at the University of Iowa. After witnessing the successful treatment of cystic fibrosis in […]
Customer Profiles
March 20, 2023

Overcoming Obstacles in Differential RNA Isoform Expression at Single Cell Resolution

One common trait among scientists is that if there is no path forward, they will create one. This is what PhD student Elisabeth Rebboah did when she needed to effectively sequence long alternative splicing isoforms across multiple samples and conditions. Most single cell RNA-Seq (scRNA-seq) approaches rely on short-read sequencing. But when isoforms resulting from […]
Customer Profiles
February 28, 2023

Investigating the Role of APOE in COVID-19 Mortality

The arrival of SARS-CoV-2 in early 2020 changed the work environment for most of us. While we were collectively getting used to social distancing, empty offices, and online meetings, Dr. Benjamin Ostendorf was embarking on a new project.  While the breadth of the COVID-19 pandemic would unfold over time, it was very soon becoming apparent […]
Customer Profiles
February 28, 2023

A Closer Look at Chromatin’s Role in Cancer Using Single Cell RNA-Seq

What causes cancer? A prevalent narrative is that a mutation in one or more critical genes causes a cell to start growing uncontrollably, eventually forming a tumor. While the mutational changes are undeniably important, it is becoming clear that they are probably not the only driver and something else must be happening in the cell […]
Customer Profiles
February 28, 2023

Alzheimer’s Disease Research: Using Single Cell RNA-Seq to Better Understand the Brain

Alzheimer’s disease (AD), the most common form of dementia, is part of the World Health Organization’s list of the top 10 leading causes of death. Despite numerous clinical trials, Alzheimer’s disease is the only member of this list that has no available drug to treat or slow the disease in any meaningful way. The advent […]

Series

Customer Profiles

Interviews with researchers about the benefits of single cell sequencing.