Our kits take you from single cell or single nuclei suspensions through sequencing straight into biological insights.
Target 100s to 1000s of genes to analyze more samples with less sequencing.
Pair guide RNAs with single cell whole transcriptomes.
Transform single cell sequencing output into understandable results.
Parse Biosciences provides researchers with the ability to perform single cell sequencing with unprecedented scale and ease.
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Comprehensive gene profiling across samples, replicates, or timepoints for most studies.
More genes detected per cell provide comprehensive results over conventional approaches.
Sequencing saturation plot generated from mouse liver samples prepared using Evercode™ WT v2.
Combine previous experimental data with full compatibility of results. We didn’t take any shortcuts or introduce bias when developing the top performing single cell RNA-Seq assay.
PBMC samples from four individual donors were prepared together to illustrate the reproducibility of the assay. The median and distribution of genes is consistent across samples.
Improvements in single cell technology have created a more predictable single cell RNA-Seq assay. Reduce sample dropout across samples and sample types - in both the single cell and single nuclei assays.
Multiplets are a nuisance of single cell RNA-Seq approaches that complicate data analysis. When the cell is the reaction vessel, issues related to multiple cells in a droplet are eliminated and it shows up in data cleanliness.
In a human-mouse species mixing experiment utilizing the WT, we detect only 1.7% multiplets - much lower than droplet-based approaches.
Fix cells or nuclei to lock in the biology until your experiment is ready. In timecourse studies, avoid uncertainty and remove batch bias by running samples collected on different days together.
Fixation locks in the biology to provide workflow flexibility. We checked a freshly prepared sample against the same sample stored for 6 months to prove stability of the fixation and reproducibility of the assay (Evercode™ WT v1 results shown).
Difficult samples or complex research questions often require a single nuclei approach. The Evercode technology works with both single nuclei sequencing (snRNA-Seq) and single cell sequencing (scRNA-Seq).
Combinatorial barcoding finally made it feasible to analyze a large number of samples with low reagent and time costs, and the data quality is top-notch. We used Parse Biosciences' kits to study the effects of BSL-3 pathogens on airway epithelia at single cell resolution. Moreover, Parse provided amazing customer support.
Lock in gene expression immediately after sample collection with a rapid fixation protocol. After fixation, samples can be stored for up to 6 months or proceed directly to barcoding.
Read more about the technology with a deeper dive into the technical details.
Review a collection of datasets that compare differences between Parse Biosciences v1 and v2 chemistries and Parse Biosciences v2 chemistry and 10x Genomics Single Cell Gene Expression v3.1.
