Technology

Discover scalable, instrument-free single cell sequencing technology from Parse Bioscience

Technology Overview


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Resources Overview

Company

Providing researchers single cell sequencing with unprecedented scale and ease

About Parse

The Smarter Single Cell Platform

Evercode gives you the power of high-throughput single cell analysis — without the trade-offs of alternative technologies. No instrument. Lower costs. More flexibility. Better data.

What Makes Evercode’s Combinatorial Barcoding Different from Other Single Cell Technologies?

Other Platforms

Most single cell platforms rely on microfluidic droplets or a physical barrier to separate cells and add barcodes. These systems require expensive instruments, complex workflows, and limit your scale.

Evercode

By fixing and permeabilizing your cells first, we turn each one into its own reaction vessel. Our split-pool barcoding process creates a unique barcode combination for each cell, without physically isolating them.

The Evercode Approach

  • No instrument required
  • Scales from 10k to over 10M cells
  • Flexible sample batching and storage
  • Clean, high-quality data

Advancing Research for 3,000+ Labs

 

Data Quality

Don’t Take Our Word for It — See the Data

Researchers trust Parse to deliver clean, high-quality single cell data. Compare Evercode’s performance side-by-side: low ambient RNA, enriched disease-relevant transcripts, fewer doublets, and minimal ribosomal or mitochondrial background.

Easier Sample Processing

Fix Now. Process Later. Run It All Together.

Fixation gives you control. Collect samples on your schedule — across days, sites, or collaborators — then process them all together when you’re ready.

No late nights. No rush. No compromises.

Whole transcriptome data, species-agnostic performance, and less batch variation.

Decrease Experimental Cost

As Low as 1¢ per Cell — or $99 per Sample

Evercode kits can be $99 per sample or 1¢ per cell as you increase throughput. With superior sensitivity and reduced ambient, mitochondrial, and ribosomal reads, every dollar goes toward meaningful data.

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~1,000,000
cells

Average Single Cell Study (2024)

More Cells per Experiment

Scale Your Cell Count, Not Your Complexity

Break free from building your experiment around fixed cartridge sizes. With Evercode’s split-pool chemistry, you choose from as low as 10,000 cells up to over 10 million in a single run, while driving your cost down to as little as $.01 per cell. More cells, less cost, all in one seamless workflow.

Fix Samples & Capture Everything

Whole Transcriptome. Whole Truth.

Evercode’s reverse transcription-based chemistry delivers full-length gene coverage with the logistical simplicity of fixation. In head-to-head tests vs. probe-based kits, Evercode detects twice as many genes—capturing more RNA biotypes—and gives consistent, RT-based measurements.

Our comparison data is based on survey results collected after the experiment was run with support from our team.

Access to On-demand Support

Not Just Support — A Scientific Partnership

From experimental design to final figures, Parse scientists help you get the most from your data. You’re never alone with Evercode.

Species-Agnostic Fixation

Fix Any Sample, From Any Species

From axolotl to zebrafish, Evercode’s fixation chemistry locks in RNA quality across tissues and organisms. Fix once, store for months, and process together for consistently high-quality data no matter what species you are working with.

Explore Datasets

Easy-to-use Data Analysis

From FASTQ to Figures — No Coding Required

o Analyze single cell RNA-seq data with a free, intuitive tool designed for scientists. Explore clusters, run differential expression, and generate publication-ready figures — all in your browser.

Lower Capital Expense

Future-Proof Your Lab—No Instrument Required

Evercode grows your science without breaking your budget. Instead of buying and upgrading hardware every few years, simply update your chemistry kits—no capital expense, no service contracts, no obsolescence. Spend less up-front and channel your funds into more experiments.

More Samples per Experiment

Multiply Your Samples, Minimize Your Effort

Break free from fixed sample lanes. Evercode’s split-pool kit includes built-in combinatorial multiplexing for up to 384 samples in one run. Whether you test 4 or 384, your cost per sample drops as you scale—no extra reagents or cartridges needed.

Minimize Hands-on Time

Your Workflow, Automated

Evercode fits into any lab setup—from manual pipetting to full liquid-handler automation. Choose the level of hands-off processing you need to boost throughput, consistency, and reproducibility.

“The speed and scale by which Parse is able to deliver these datasets is truly amazing and will accelerate the pace of discovery.”
Dr. Fabian Theis
Dr. Fabian Theis
Director of the Institute for Computational Biology, Helmholtz Munich

Evercode™ Products

Scalable single cell sequencing without the instrument. Each kit provides end-to-end solution reagents and intuitive analysis software.

Evercode™ Immune Profiling

Explore a wide variety of immunological applications through Evercode TCR and Evercode BCR. Each kit takes you from samples through sequencing directly to insights into the immune repertoire.

Evercode TCR and Evercode BCR are the only fixation-based scRNA-Seq Immune profiling assays available.

 

We’re your partners in single cell

Reach out for a quote or for help planning your next experiment. Get started today
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