Company

Technology

Discover scalable, instrument-free single cell sequencing technology from Parse Bioscience

Technology Overview


Resources

Explore our collection of resources to learn more about technology and its applications from leading researchers

Resources Overview

Company

Providing researchers single cell sequencing with unprecedented scale and ease

About Parse

Webinars

Watch webinars on Evercode™ technology and its applications.

Gene Capture Immune Profiling Tcr

Expanding Single Cell Capabilities with Immune Profiling and Targeted Gene Capture

In this webinar, you will learn about Evercode TCR for immune profiling and Gene Capture for even greater scalability. You will also learn more about Parse’s foundational technology platform, which enables single cell RNA sequencing with no microfluidics instrument required.

Anastasia Potts, PhD
Anastasia Potts, PhD
Senior Product Manager
Parse Biosciences
Charlie Roco, PhD
Charlie Roco, PhD
CTO and Cofounder
Parse Biosciences
Watch recorded webinar
Cancer

Using Single Cell RNA Sequencing (scRNA-Seq) to Examine What Makes Cancer Possible

In this webinar, Dr. Katerina Gurova, Roswell Park Cancer Institute, describes how she used scRNA-Seq to examine whether the transition between one epigenetic state into another makes cells vulnerable to oncogene induced transformation.

Katerina Gurova, PhD
Katerina Gurova, PhD
Associate Professor
Roswell Park Comprehensive Cancer Center
Watch recorded webinar
Alzheimers Brain

Single-cell Transcriptomic Landscape in Alzheimer’s Disease

The gene-regulatory landscape of the brain is highly dynamic in health and disease, coordinating a menagerie of biological processes across distinct cell types. Understanding these regulatory programs requires a holistic experimental and analytical approach. Here, we present a single-cell study of 380,000 nuclei in late-stage Alzheimer’s Disease (AD) using parse biosciences whole transcriptome kit, profiling gene expression in thousands of genes and uncovering vast neuronal and glial heterogeneity in late-stage AD.

Vivek Swarup, PhD
Vivek Swarup, PhD
Assistant Professor
UC Irvine
Watch recorded webinar
WT

High Sensitivity Single Cell RNA Sequencing with Evercode Whole Transcriptome v2

Single cell RNA sequencing has become a core tool for researchers to understand biology. As scRNA-seq has become more ubiquitous, many applications demand higher scalability and sensitivity. To meet this need, we developed the Evercode Whole Transcriptome v2 solution, a combinatorial barcoding workflow for scRNA-seq with dramatically improved sensitivity, robustness, and unbiased gene expression.

Charlie Roco, PhD
Charlie Roco, PhD
CTO and Cofounder
Parse Biosciences
Watch recorded webinar

Mapping and Modeling the Genomic Basis of Differential RNA Isoform Expression at Single-cell Resolution

In this informative webinar recording, Elisabeth Rebboah, UC Irvine, discusses overcoming these obstacles to perform differential RNA isoform expression at single-cell resolution using the split pool combinatorial barcoding protocol from Parse Biosciences along with a combination of short read sequencing to characterize cell types and long read sequencing to reveal full-length isoforms.

Elisabeth Rebboah
Elisabeth Rebboah
PhD Student
UC Irvine
Watch recorded webinar
WT

Single Cell RNA-Seq on the Frontlines: High Multiplex and Time-course Experiments Expand Utility

Experimental designs are growing alongside the increased throughput requirements of single-cell RNA-Seq assays. Replicates, disease states, and time-course designs dramatically increase the number of samples and the burden of information gleaned from a single experiment. Alongside these considerations is a substantial increase in the implications of the results. Our speakers discuss the ramifications of higher-order studies on needs for data quality, throughput attenuation, and sample longevity.

Alejandro Pezzulo, MD
Alejandro Pezzulo, MD
Assistant Professor
University of Iowa
Watch recorded webinar
WT Crispr Gene Capture Immune Profiling WT

Scaling Your scRNA-Seq Experiments with Parse Biosciences’ Evercode

The average number of cells profiled in single cell RNA sequencing (scRNA-Seq) experiments has doubled each year since 2015. Yet traditional scRNA-Seq technologies have not scaled well nor do they provide straightforward implementation. Join us for a webinar with Parse Biosciences CTO, Charlie Roco. In it, he describes how straightforward it is to get started and scale with Parse’s combinatorial barcoding technology, Evercode.

Charlie Roco, PhD
Charlie Roco, PhD
CTO and Cofounder
Parse Biosciences
Watch recorded webinar
Crispr

Perturbing and Tracing Tumor Lineages Resistant to NK Cell-Mediated Killing

During the webinar, Dr. Cong and Yuanhao (Jerry) Qu discussed the advancements made possible by CRISPR Detect. They discuss a new single-cell “perturb and trace” system that combines multiplexed Cas12a perturbations with a machine learning-optimized, single-cell evolvable barcoding system.

Le Cong, PhD
Le Cong, PhD
Assistant Professor
Stanford University School of Medicine
Yuanhao (Jerry) Qu
Yuanhao (Jerry) Qu
PhD Student
Stanford University
Anastasia Potts, PhD
Anastasia Potts, PhD
Senior Product Manager
Parse Biosciences
Watch recorded webinar
WT

Sox9 links biliary maturation to branching morphogenesis

Type 2 diabetes (T2D) is a known risk factor for cerebrovascular diseases including Alzheimer’s disease (AD), and vascular dementia (VaD). Yet, our understanding of the mechanisms whereby T2D contributes to neurodegeneration and VaD remains poorly defined. In this study, we utilized the db/db murine model of T2D and single nuclei RNA sequencing to determine the effect of T2D on endothelial cell-specific transcriptomic changes in the hippocampus, an important brain memory center.

Hannah Hrncir
Hannah Hrncir
PhD Candidate
Emory University
Watch recorded webinar
WT

snRNAseq reveals hippocampal endothelial dysfunction and impaired permeability in diabetic mice

Type 2 diabetes (T2D) is a known risk factor for cerebrovascular diseases including Alzheimer’s disease (AD), and vascular dementia (VaD). Yet, our understanding of the mechanisms whereby T2D contributes to neurodegeneration and VaD remains poorly defined. In this present work, we utilized the db/db murine model of T2D and single nuclei RNA sequencing to determine the effect of T2D on endothelial cell-specific transcriptomic changes in the hippocampus, an important brain memory center.

Saivageethi Nuthikattu
Saivageethi Nuthikattu
Assistant Project Scientist
UC Davis
Watch recorded webinar

Getting Started with Single Cell Sequencing (Central European Time)

What You Will Learn:

  • Learn about the history and evolution of scRNA-seq
  • Understand how it could be used in your research
  • Gain an understanding of the technologies available
  • Receive a high level overview of the scRNA-seq workflow and important considerations before getting started
Natalia Juiz
Natalia Juiz
Senior Field Application Scientist
Parse Biosciences
Watch recorded webinar

Getting Started with Single Cell Sequencing (Pacific Time)

What You Will Learn:

  • Learn about the history and evolution of scRNA-seq
  • Understand how it could be used in your research
  • Gain an understanding of the technologies available
  • Receive a high level overview of the scRNA-seq workflow and important considerations before getting started
Colleen Palmateer, PhD
Colleen Palmateer, PhD
Field Application Scientist
Parse Biosciences
Watch recorded webinar
Bioinformatics Data Analysis Getting Started

Getting Started with scRNA-seq: Sequencing and Data Analysis

Single Cell RNA Sequencing (scRNA-seq) is helping researchers uncover new insights in ways not possible with traditional bulk RNA sequencing methods. For researchers interested in learning more or just getting started, we’ve developed a series of three educational webinars focused on demystifying scRNA-seq.

In our third and final webinar in the series, we described unique considerations for sequencing and data analysis when doing scRNA-seq experiments.

Brian Davis
Brian Davis
Field Application Scientist
Parse Biosciences
Watch recorded webinar
Experimental Design Getting Started Sample Prep

Single Cell RNA Sequencing Experimental Design and Sample Preparation

Single Cell RNA Sequencing (scRNA-seq) is helping researchers uncover new insights in ways not possible with traditional bulk RNA sequencing methods. For researchers interested in learning more or just getting started, we’ve developed a series of three educational webinars focused on demystifying scRNA-seq.

In our second webinar of the series, we described unique considerations for experimental design and sample preparation when doing scRNA-seq projects.

Andria Doty, PhD
Andria Doty, PhD
Senior Field Application Scientist
Parse Biosciences
Watch recorded webinar
Getting Started

The Origins and Fundamentals of Single Cell RNA Sequencing

Single Cell RNA Sequencing (scRNA-seq) is helping researchers uncover new insights in ways not possible with traditional bulk RNA sequencing methods. For researchers interested in learning more or just getting started, we’ve developed a series of three educational webinars focused on demystifying scRNA-seq.

In our first webinar of the series, we explored scRNA-seq’s origins and what research questions it can help you answer.

Colleen Palmateer, PhD
Colleen Palmateer, PhD
Field Application Scientist
Parse Biosciences
Watch recorded webinar

Unlocking the Antigen Presenting Potential of Synoviocytes with Evercode Single Cell

In this webinar, Robert Lochhead from the Medical College of Wisconsin, explains his use of the Parse single cell RNAseq and other downstream in vitro validation methods, showing that IFN-gamma-stimulated fibroblast-like synoviocytes are inducible APCs.

Robert Lochhead
Robert Lochhead
Assistant Professor
The Medical College of Wisconsin
Watch recorded webinar

Mapping Interactomes: Precision Health through AI, Single-Cell, and Spatial Biology

What You Will Learn:

  • From FASTQ to Publication-Ready Figures: Learn how you can progress from raw data to insightful, publication-ready figures with just a few clicks with Trailmaker.
  • Cutting-Edge Research: Get insights into the groundbreaking work being conducted by Kevin Matthew Byrd and his team.
Kevin Matthew Byrd, DDS, PhD
Kevin Matthew Byrd, DDS, PhD
Assistant Professor
University of North Carolina at Chapel Hill
Vicky Morrison, PhD
Vicky Morrison, PhD
Senior Product Manager, Software
Parse Biosciences
Watch recorded webinar
WT Mouse Brain

Distressed: Identifying the mechanisms behind stress induced fear and anxiety

In this webinar, Ethan Goodman explains how single-cell sequencing was used to identify the key cells and critical signaling pathways in the brain responsible for a heightened fear response due to social stress in mice, providing insights into the molecular mechanisms underlying stress-related behavioral changes.

Ethan J. Goodman
Ethan J. Goodman
PhD Student
Ohio State University
Watch recorded webinar
BCR TCR

Single Cell Immune Profiling at Unprecedented Scale

Join us for an informative webinar in which we overview our new single cell BCR and TCR profiling products which enable immune profiling at unprecedented scale. We are also excited to showcase the work of the Reticker-Flynn Lab at Stanford and how they are using single cell immune profiling to understand the process by which tumors evade the immune system and metastasize to invade the body.

Nathan Reticker-Flynn, PhD
Nathan Reticker-Flynn, PhD
Stanford University
Assistant Professor, PI
Cort Breur
Cort Breur
PhD Student
Stanford University
Charlie Roco, PhD
Charlie Roco, PhD
CTO and Cofounder
Parse Biosciences
Watch recorded webinar
WT Crispr Gene Capture Immune Profiling WT

Scaling Your scRNA-Seq Experiments with Parse Biosciences’ Evercode

The average number of cells profiled in single cell RNA sequencing (scRNA-Seq) experiments has doubled each year since 2015. Yet traditional scRNA-Seq technologies have not scaled well nor do they provide straightforward implementation. Join us for a webinar with Parse Biosciences CTO, Charlie Roco. In it, he describes how straightforward it is to get started and scale with Parse’s combinatorial barcoding technology, Evercode.

Charlie Roco, PhD
Charlie Roco, PhD
CTO and Cofounder
Parse Biosciences
Watch recorded webinar
WT

High Sensitivity Single Cell RNA Sequencing with Evercode Whole Transcriptome v2

Single cell RNA sequencing has become a core tool for researchers to understand biology. As scRNA-seq has become more ubiquitous, many applications demand higher scalability and sensitivity. To meet this need, we developed the Evercode Whole Transcriptome v2 solution, a combinatorial barcoding workflow for scRNA-seq with dramatically improved sensitivity, robustness, and unbiased gene expression.

Charlie Roco, PhD
Charlie Roco, PhD
CTO and Cofounder
Parse Biosciences
Watch recorded webinar