EVERCODE™ IMMUNE PROFILING

Single Cell Immune Profiling: Streamlined

Paired whole transcriptome and immune repertoire from the same cells, now with a streamlined workflow and improved cell recovery.

Resolve immune cell state and clonotype within the same experiment

Profile gene expression alongside TCR or BCR repertoire to connect cell state, diversity, and function within immune populations, now with a more efficient, streamlined workflow.

Greater efficiency for immune profiling with Evercode v4

→ Capture more cells from every sample
→ Detect more genes and transcripts
→ Use whole transcriptome sequencing more efficiently
→ Streamline your workflow with bead-based separation

Evercode v4 improves workflow efficiency while maintaining trusted immune profiling performance across key metrics, enabling a seamless transition to a more streamlined assay.

Trusted single cell TCR profiling performance

Evercode TCR captures paired TCR α and β CDR3 sequences alongside whole transcriptome data from the same cells.

This enables analysis of clonotype, gene expression, and cell state together, placing T cell receptors in their full cellular context.

Consistent clonotype detection

Top clonotypes identified in CMV-expanded T cells show strong concordance across v3 and v4 chemistries, supporting consistent clonotype detection.

Robust TCR CDR3 detection and pairing

High detection of TCR α CDR3 (87%) and TCR β CDR3 (77%) sequences with strong paired CDR3 recovery (64%) supports confident clonotype identification.

High-confidence BCR profiling

Evercode BCR captures paired heavy and light chain CDR3 and full-length sequences alongside whole transcriptome data from the same cells.

This enables analysis of B cell clonality, diversity, and gene expression together, connecting receptor diversity to cell identity.

High BCR CDR3 Detection and Pairing

High detection of heavy (97%) and light (95%) chain CDR3 sequences, along with strong paired CDR3 recovery (92%), supports confident BCR profiling.

High full-length heavy and light chain recovery

80% full-length heavy and 69% full-length light chain recovery for confident downstream analysis.

Whole Transcriptome

Immune Profiling

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