Company

Technology

Discover scalable, instrument-free single cell sequencing technology from Parse Bioscience

Technology Overview


Resources

Explore our collection of resources to learn more about technology and its applications from leading researchers

Resources Overview

Company

Providing researchers single cell sequencing with unprecedented scale and ease

About Parse

Technology

Discover scalable, instrument-free single cell sequencing technology from Parse Bioscience

Technology Overview

Products

Gain biological insights from these sequencing solutions

Products Overview

Webinars

Watch webinars on Evercode™ technology and its applications.

All Webinars

Sox9 links biliary maturation to branching morphogenesis

Type 2 diabetes (T2D) is a known risk factor for cerebrovascular diseases including Alzheimer’s disease (AD), and vascular dementia (VaD). Yet, our understanding of the mechanisms whereby T2D contributes to neurodegeneration and VaD remains poorly defined. In this study, we utilized the db/db murine model of T2D and single nuclei RNA sequencing to determine the effect of T2D on endothelial cell-specific transcriptomic changes in the hippocampus, an important brain memory center.

Hannah Hrncir
Hannah Hrncir
Emory University
Watch recorded webinar
WT

snRNAseq reveals hippocampal endothelial dysfunction and impaired permeability in diabetic mice

Type 2 diabetes (T2D) is a known risk factor for cerebrovascular diseases including Alzheimer’s disease (AD), and vascular dementia (VaD). Yet, our understanding of the mechanisms whereby T2D contributes to neurodegeneration and VaD remains poorly defined. In this present work, we utilized the db/db murine model of T2D and single nuclei RNA sequencing to determine the effect of T2D on endothelial cell-specific transcriptomic changes in the hippocampus, an important brain memory center.

Saivageethi Nuthikattu
Saivageethi Nuthikattu
Watch Recorded Webinar
WT

Redefining Single Cell with Evercode Whole Transcriptome v3

In this webinar, we showcased the latest version of our flagship technology, Evercode Whole Transcriptome v3.

What you’ll learn by watching:

  • More about Evercode split-pool combinatorial barcoding as the leading choice for single cell research.
  • What this product update can mean for your research.
  • How this update stacks up against other available technologies.
Alex Rosenberg, PhD
Alex Rosenberg, PhD
CEO and Co-founder
Parse Biosciences
Watch Recorded Webinar
WT

Social Housing and Daylength Impact Hippocampal Transcriptome of a Seasonally Prosocial Species

Meadow voles are a seasonally prosocial species, displaying stark differences in social tolerance and bonding between summer and winter. In this webinar, researcher Matt Davis, UC Berkeley, describes how he used single cell RNA-seq to probe how seasonal cues impact the composition and transcriptional phenotypes of diverse hippocampal cell types.

Matt Davis
Matt Davis
Watch recorded webinar
Experimental Design Getting Started Sample Prep

Single Cell RNA Sequencing Experimental Design and Sample Preparation

Single Cell RNA Sequencing (scRNA-seq) is helping researchers uncover new insights in ways not possible with traditional bulk RNA sequencing methods. For researchers interested in learning more or just getting started, we’ve developed a series of three educational webinars focused on demystifying scRNA-seq.

In our second webinar of the series, we described unique considerations for experimental design and sample preparation when doing scRNA-seq projects.

Andria Doty, PhD
Andria Doty, PhD
Senior Field Application Scientist
Parse Biosciences
Watch recorded webinar
Getting Started

The Origins and Fundamentals of Single Cell RNA Sequencing

Single Cell RNA Sequencing (scRNA-seq) is helping researchers uncover new insights in ways not possible with traditional bulk RNA sequencing methods. For researchers interested in learning more or just getting started, we’ve developed a series of three educational webinars focused on demystifying scRNA-seq.

In our first webinar of the series, we explored scRNA-seq’s origins and what research questions it can help you answer.

Colleen Palmateer, PhD
Colleen Palmateer, PhD
Field Application Scientist
Parse Biosciences
Watch recorded webinar
Brain

Spatial Heterogeneity of Transcriptomic Variability in Glioblastoma

In this webinar, Federico Gaiti, PhD, from Princess Margaret Cancer Centre, presents information on spatial intra-tumoral heterogeneity of malignant and immune cells in glioblastoma and how the Parse technology is helping Dr. Gaiti’s team advance their work and knowledge in GBM.

Federico Gaiti, PhD
Federico Gaiti, PhD
Assistant Professor
Princess Margaret Cancer Centre
Watch Webinar Recording
Bioinformatics Data Analysis

Identifying Distinct Cellular Programs from Single Cell Datasets Using Topyfic

In this webinar, Narges Rezaie, a PhD candidate from the University of California, Irvine, demonstrates how to use topic modeling to identify repeated patterns in single cell data.

Narges Rezaie
Narges Rezaie
PhD Student
UC Irvine
Watch Webinar Recording
Crispr

Perturbing and Tracing Tumor Lineages Resistant to NK Cell-Mediated Killing

During the webinar, Dr. Cong and Yuanhao (Jerry) Qu discussed the advancements made possible by CRISPR Detect. They discuss a new single-cell “perturb and trace” system that combines multiplexed Cas12a perturbations with a machine learning-optimized, single-cell evolvable barcoding system.

Watch Webinar Recording
Alzheimers

Single Cell RNA-seq Sheds Light on the Role of Microglia in Alzheimer’s Disease

In this webinar, Dr. Swarup, demonstrates the protective functions of microglia in reducing CAA, blood-brain barrier dysfunction, and brain calcification. Examination of human AD tissue and iPSC-microglia demonstrates that microglia phagocytose calcium crystals and is impaired by the loss of the AD risk gene, TREM2.

Vivek Swarup, PhD
Vivek Swarup, PhD
Assistant Professor
UC Irvine
Watch recorded webinar
Crispr Gene Capture Immune Profiling WT

Scaling Your scRNA-Seq Experiments with Parse Biosciences’ Evercode

The average number of cells profiled in single cell RNA sequencing (scRNA-Seq) experiments has doubled each year since 2015. Yet traditional scRNA-Seq technologies have not scaled well nor do they provide straightforward implementation. Join us for a webinar with Parse Biosciences CTO, Charlie Roco. In it, he describes how straightforward it is to get started and scale with Parse’s combinatorial barcoding technology, Evercode.

Charlie Roco, PhD
Charlie Roco, PhD
CTO and Cofounder
Parse Biosciences
Watch recorded webinar

Sox9 links biliary maturation to branching morphogenesis

Type 2 diabetes (T2D) is a known risk factor for cerebrovascular diseases including Alzheimer’s disease (AD), and vascular dementia (VaD). Yet, our understanding of the mechanisms whereby T2D contributes to neurodegeneration and VaD remains poorly defined. In this study, we utilized the db/db murine model of T2D and single nuclei RNA sequencing to determine the effect of T2D on endothelial cell-specific transcriptomic changes in the hippocampus, an important brain memory center.

Hannah Hrncir
Hannah Hrncir
Emory University
Watch recorded webinar
WT

snRNAseq reveals hippocampal endothelial dysfunction and impaired permeability in diabetic mice

Type 2 diabetes (T2D) is a known risk factor for cerebrovascular diseases including Alzheimer’s disease (AD), and vascular dementia (VaD). Yet, our understanding of the mechanisms whereby T2D contributes to neurodegeneration and VaD remains poorly defined. In this present work, we utilized the db/db murine model of T2D and single nuclei RNA sequencing to determine the effect of T2D on endothelial cell-specific transcriptomic changes in the hippocampus, an important brain memory center.

Saivageethi Nuthikattu
Saivageethi Nuthikattu
Watch Recorded Webinar
Bioinformatics Data Analysis Getting Started

Getting Started with scRNA-seq: Sequencing and Data Analysis

Single Cell RNA Sequencing (scRNA-seq) is helping researchers uncover new insights in ways not possible with traditional bulk RNA sequencing methods. For researchers interested in learning more or just getting started, we’ve developed a series of three educational webinars focused on demystifying scRNA-seq.

In our third and final webinar in the series, we described unique considerations for sequencing and data analysis when doing scRNA-seq experiments.

Brian Davis
Brian Davis
Field Application Scientist
Parse Biosciences
Watch recorded webinar
Experimental Design Getting Started Sample Prep

Single Cell RNA Sequencing Experimental Design and Sample Preparation

Single Cell RNA Sequencing (scRNA-seq) is helping researchers uncover new insights in ways not possible with traditional bulk RNA sequencing methods. For researchers interested in learning more or just getting started, we’ve developed a series of three educational webinars focused on demystifying scRNA-seq.

In our second webinar of the series, we described unique considerations for experimental design and sample preparation when doing scRNA-seq projects.

Andria Doty, PhD
Andria Doty, PhD
Senior Field Application Scientist
Parse Biosciences
Watch recorded webinar
Getting Started

The Origins and Fundamentals of Single Cell RNA Sequencing

Single Cell RNA Sequencing (scRNA-seq) is helping researchers uncover new insights in ways not possible with traditional bulk RNA sequencing methods. For researchers interested in learning more or just getting started, we’ve developed a series of three educational webinars focused on demystifying scRNA-seq.

In our first webinar of the series, we explored scRNA-seq’s origins and what research questions it can help you answer.

Colleen Palmateer, PhD
Colleen Palmateer, PhD
Field Application Scientist
Parse Biosciences
Watch recorded webinar

Single Cell Immune Profiling at Unprecedented Scale

Join us for an informative webinar in which we overview our new single cell BCR and TCR profiling products which enable immune profiling at unprecedented scale. We are also excited to showcase the work of the Reticker-Flynn Lab at Stanford and how they are using single cell immune profiling to understand the process by which tumors evade the immune system and metastasize to invade the body.

Charlie Roco, PhD
Charlie Roco, PhD
CTO and Cofounder
Parse Biosciences
Cort Breur
Cort Breur
PhD Student
Stanford University
Nathan Reticker-Flynn, PhD
Nathan Reticker-Flynn, PhD
Stanford University
Assistant Professor, PI
Register for upcoming webinar
Crispr Gene Capture Immune Profiling WT

Scaling Your scRNA-Seq Experiments with Parse Biosciences’ Evercode

The average number of cells profiled in single cell RNA sequencing (scRNA-Seq) experiments has doubled each year since 2015. Yet traditional scRNA-Seq technologies have not scaled well nor do they provide straightforward implementation. Join us for a webinar with Parse Biosciences CTO, Charlie Roco. In it, he describes how straightforward it is to get started and scale with Parse’s combinatorial barcoding technology, Evercode.

Charlie Roco, PhD
Charlie Roco, PhD
CTO and Cofounder
Parse Biosciences
Watch recorded webinar
WT

High Sensitivity Single Cell RNA Sequencing with Evercode Whole Transcriptome v2

Single cell RNA sequencing has become a core tool for researchers to understand biology. As scRNA-seq has become more ubiquitous, many applications demand higher scalability and sensitivity. To meet this need, we developed the Evercode Whole Transcriptome v2 solution, a combinatorial barcoding workflow for scRNA-seq with dramatically improved sensitivity, robustness, and unbiased gene expression.

Charlie Roco, PhD
Charlie Roco, PhD
CTO and Cofounder
Parse Biosciences
Watch recorded webinar