Parse Biosciences at ASHG 2024
We’re excited to connect with you at ASHG and dive deeper into your research while exploring the exciting world of single cell! Swing by Booth #703 anytime, or join us at our events to spark conversations and share insights. We can’t wait to see you there!
Sessions
Accelerate your single cell research with the latest advances from Parse Biosciences
In our CoLab session, Chief Technology Officer Charlie Roco, PhD, will unveil exciting updates to our portfolio of single cell solutions. Highlights include advancements in Evercode Whole Transcriptome, Evercode TCR, Evercode BCR, and Trailmaker, all designed to make single cell more accessible and powerful than ever.
Using single cell to explore the impact of genetic diversity on cell type- and state-specific gene expression in mice
In this session, Elisabeth Rebboah, PhD, from the Mortazavi Lab at UC Irvine, discusses her recent work on the impact of genetic diversity on cell type- and state-specific gene expression in mice.
Through an extensive study of various mouse strains and tissue types, significant diversity in gene expression profiles was uncovered. Single Cell Sequencing analysis of millions of cells revealed that different tissues exhibit varying levels of transcriptional variation due to strain differences, with specific impacts on cell types (e.g., neurons show less variation compared to glial cells and hepatocytes). Rebboah’s findings indicate that genetic diversity correlates with transcriptional variation, with wild-derived strains exhibiting the most differential expression. Additionally, while most cell types show significant variation in wild strains, at least one cell state specific to a common lab strain was identified, which is linked to a known phenotype: activated muscle stem cells in A/J mice, predisposed to muscular dystrophy.
Single Cell-ebration
Join Parse Biosciences’ unforgettable third annual Single Cell-ebration! Enjoy an evening of drinks, delicious food, and engaging entertainment, all while connecting with fellow scientists in a cell-ebratory atmosphere. The event will be held just a short 5-minute walk from the Denver Convention Center at the Studio Loft, 980 14th Street, Denver, 80202. The Parse team can’t wait to cell-ebrate with you!
Poster Presentations
High throughput single-cell TCR sequencing method on aging mouse T cells and antigen stimulation in human T cell powered by split pool combinatorial barcoding technology
Improvements in Combinatorial scRNA Sequencing that Enable Scaling to Hundreds of Samples and Millions of Cells in a Single Experiment
Simultaneous profiling of 1M single-cell BCRs and whole transcriptomes from diseased and healthy B cells in a single experiment using split-pool combinatorial barcoding
Enabling low cell input and high throughput processing of cell and nuclei fixation for single-cell RNA profiling using combinatorial barcoding
Visit us at Booth #703
Stop by to chat with our staff about the Evercode technology, join our flash talks at our in-booth theatre, and pick up some of the coolest swag at the conference!