Our kits take you from single cell or single nuclei suspensions through sequencing straight into biological insights.
Target 100s to 1000s of genes to analyze more samples with less sequencing.
Pair guide RNAs with single cell whole transcriptomes.
Transform single cell sequencing output into understandable results.
Parse Biosciences provides researchers with the ability to perform single cell sequencing with unprecedented scale and ease.
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Glioblastoma remains the most common form of brain cancer, exhibiting enormous heterogeneity in the tumor and immune compartments, within both the same tumor and between patients. To characterize this heterogeneity within tumor samples and in vitro models, we utilized the Parse Evercode V2 assay to profile whole cells processed from a patient-derived neurosphere line, alongside nuclei isolated from a piece of flash-frozen glioblastoma tissue. Clustering of cells using Parse Analysis Pipeline revealed multiple distinct cell types from all samples, as demonstrated in the UMAP below.
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All-Well Analysis Summary Report* Cell Vehicle Analysis Summary Report Cell Treated Analysis Summary Report Nuclei Sphere Analysis Summary Report Nuclei Tissue Analysis Summary Report
* The plate heatmap of the all-well summary, wells 7-10 are empty, having been removed due to patient privacy.
