Area of Interest: Developmental Biology

A collection of Parse Biosciences resources including publications, webinars, datasets, product literature, application and technical notes relating to developmental biology.

Total posts found: 61

StrataChip: a microphysiological system capturing dynamic keratinocyte fate and mechanical transitions during human epidermal morphogenesis

Increases in BCL2L1 and ID1 dosage synergistically drive fate bias and competitive advantage in human pluripotent stem cells

A single-cell eQTL atlas of the developing human brain

Z-DNA formation regulates the totipotent-like state and primes Zscan4-dependent chromatin compartmentalization

Cellular diversity of the developing chick trigeminal ganglion at single-cell resolution

Single nuclei transcriptomics reveals programming of metabolic functions by embryonic temperature in the developing Atlantic salmon liver

Calcium dynamics tune timing of developmental transitions to generate evolutionarily divergent axon tract lengths

Systematic scRNA-seq screens profile neural organoid response to morphogens

KMT2D-deficiency destabilizes lineage progression in immature neural progenitors

Spatiotemporal Atlas of Heart Development Reveals Blood-Flow-Dependent Cellular, Structural, Metabolic, and Spatial Remodeling

A Single Cell Atlas of the Newt Iris During Lens Regeneration

Developmental and transcriptional programs that define the initiation of the forelimb

Hypoxia promotes airway differentiation in the human lung epithelium

Evolutionary remodeling of the ventral retina enables aerial vision in the four-eyed fish Anableps anableps

Foxi2 and Sox3 are master transcription regulators that control ectoderm germ layer specification in Xenopus

An advanced head-to-tail mouse embryo model with hypoxia-mediated neural patterning

Morphogenetic ovarian modules for oocyte production from germline stem cells

Morphogenetic ovarian modules for oocyte production from germline stem cells

Emergence of Genetic Sex Determination in an Environmentally Sex-Determined Animal

Controlling nephron precursor differentiation to generate proximal-biased kidney organoids with emerging maturity

Initiation of meiosis from human iPSCs under defined conditions through identification of regulatory factors

Stress Sensitization of Neurons in the Dentate Gyrus Is Dependent on Neuronal Interleukin-1 Receptor Signaling and Is Associated with Increased Synaptic Plasticity, Perineuronal Nets, and Excitatory/Inhibitory Input Imbalance

Dichotomous transcriptome divergence at the cell-type level between the Drosophila male and female germlines

An advanced head-to-tail mouse embryo model with hypoxia-mediated neural patterning

Maternal Undernutrition Exacerbates Effects of Ambient Heat during Pregnancy in Mice

Axial Nephron Fate Switching Demonstrates a Plastic System Tunable on Demand

Z-DNA formation induces the totipotent-like state and primes Zscan4-dependent chromatin compartmentalization

Fast-tracking Antibody Discovery with Evercode Transgenic Mouse BCR

Integrative multi-omics analysis of Polypterus fin regeneration reveals shared and derived fin and limb regeneration mechanisms

Sox9 inhibits Activin A to promote biliary maturation and branching morphogenesis

Foxi2 and Sox3 are master regulators controlling ectoderm germ layer specification

A Novel XACT lncRNA Transcript with Functions Transcending X-Chromosome Inactivation

Single-cell RNA sequencing identifies CXADR as a fate determinant of the placental exchange surface

Defining and Controlling Axial Nephron Patterning in Human Kidney Organoids with Synthetic Wnt-Secreting Organizers

Exploring the Impact of Genetic Diversity on Gene Expression in Mice

Effects of oxycodone on placental lineages: Evidence from the transcriptome profile of mouse trophoblast giant cells

Loss of 18q alters TGFβ signalling affecting anteroposterior neuroectodermal fate in human embryonic stem cells

Zebrafish models of human-duplicated SRGAP2 reveal novel functions in microglia and visual system development

Dissecting the regulatory logic of specification and differentiation during vertebrate embryogenesis

Stepwise developmental mimicry generates proximal-biased kidney organoids

Gene regulatory landscape of cerebral cortex folding

The ENCODE mouse postnatal developmental time course identifies regulatory programs of cell types and cell states

Induction of Meiosis from Human Pluripotent Stem Cells

An Atlas of spider development at single-cell resolution provies new insights into arthropod embryogensis

Multi-omic analysis of guided and unguided forebrain organoids reveal differences in cellular composition and metabolic profiles

Loss of UBE3A impacts both neuronal and non-neuronal cells in human cerebral organoids

Polycomb Repressive Complex 1.1 Component, BCOR, Promotes Syncytiotrophoblast Differentiationin Mice and Humans

Loss of p73 Expression Contributes to Chronic Obstructive Pulmonary Disease

Single-nuclei transcriptomics highlights the lasting impact of embryonic temperature on Atlantic salmon

Sox9 links biliary maturation to branching morphogenesis

Dystrophin deficiency impairs cell junction formation during embryonic myogenesis

Germline ablation achieved via CRISPR/Cas9 targeting of NANOS3 in bovine zygotes

Localized T3 production modifies the transcriptome and promotes the hepatocyte-like lineage in iPSC-derived hepatic organoids

A dynamic in vitro model of Down Syndrome neurogenesis with Trisomy 21 gene dosage correction

Directed Differentiation of Human iPSCs to Functional Ovarian Granulosa-Like Cells via Transcription Factor Overexpression

Technical Performance of CRISPR Detect in Cell Lines

Performance of Evercode™ WT in Neonatal Mouse Heart Cells

Transcript and Gene Detection in Embryonic E18 Mouse Brain

Joint profiling of gene expression and chromatin accessibility during amphioxus development at single-cell resolution

A comprehensive analysis of gene expression changes in a high replicate and open-source dataset of differentiating hiPSC-derived cardiomyocytes

Redefining the Etiologic Landscape of Cerebellar Malformations